Jean Moisson, ancestor to Comte Georges de Vogüé, first built the domaine in the 15^th century along with the church of Chambolle-Musigny. The church still holds several artworks depicting members of the Moisson family today. The Vogüé family’s name was first recorded in Burgundy in 1766, when Catherine Bouhier de Versalieu married Cerice François Melchior de Vogüé, originally from the Ardèche, where there is still a commune named Vogüé. Impressively, the family have managed to maintain ownership of the domaine throughout its history, including the French Revolution of 1789 — sadly, many other domaines suffered greatly during this period and were unable to retain their estates. 

In 1925, Comte Georges de Vogüé inherited the vineyards from his father, Comte Arthur de Vogüé and subsequently changed the domaine’s name. Today, Comte George’s granddaughters, Claire and Marie, represent the current owners after inheriting the vineyards from their mother (Comte George’s daughter) in 2002. 

The triumvirate of François Millet (appointed in 1986), Eric Bourgogne (appointed in 1988) and Jean-Luc Pépin (appointed in 1996) ran the winemaking, viticultural and commercial aspects of the domaine over what we should now call the previous generation. In 2021, Jean Lupatelli joined the domaine as Head Winemaker and has since expanded his responsibility to include the commercial aspect as of summer 2025. He is supported in the vineyards by Vincent Mahalin.